Bus
Take the bus 858 at the station Prague, Prague Hradčanská .
The journey takes approximately 1 h 20 min. Ticket price is about 3–5 EUR. The travel distance is 94 km.
Carrier is FlixBus.
Get off at the Chomutov
Train
Take the train 608 at the station Praha Hlavni Nadrazi .1
The journey takes approximately 2 h 22 min. Ticket price is about 8–13 EUR. The travel distance is 173 km.
Carrier is Czech Railways (ČD).
Get off at the Chomutov Mesto
Taxi
By taxi
It is only about 72 minutes by taxi from the Prague to Chomutov. The distance is 93 km. A one-way journey by taxi costs approximately 100-130 EUR
Check taxi prices on the KiwiTaxi.Drive
In a rental car
The drive will take 1 h 12 min.. The distance between Prague and Chomutov is 93 km. You will use 7 liters of gasoline at a cost of €9.1.
See on this site which rental company has the best deal.