Bus

Take the bus 720255 at the station Brno Zvonařka .

The journey takes approximately 4 h 2 min. Ticket price is about 13–18 EUR. The travel distance is 196 km.

Carrier is Tour Bus.

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Get off at the České Budějovice
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Train

Take the train 652 at the station Brno Hlavni Nadrazi .1

The journey takes approximately 4 h 14 min. Ticket price is about 10–18 EUR. The travel distance is 231 km.

Carrier is Czech Railways (ČD).

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Get off at the Ceske Budejovice
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Drive

In a rental car

The drive will take 2 h 19 min.. The distance between Brno and Ceske Budejovice is 216 km. You will use 17 liters of gasoline at a cost of €22.1.

See on this site which rental company has the best deal.

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